A man died after taking Chloroquine dose in Arizona

A man died after taking Chloroquine dose in Arizona

As COVID19 sweeps across all the world and the hospitals are prepare for an influx of patients.
Researchers are working to figure out if any drugs currently on the market can be used to
combat the illness. They’ve identified a number of candidates, including chloroquine, the drug
that President Donald Trump incorrectly said had been approved by the FDA as a COVID-19
treatment. But there’s nowhere near enough evidence yet to indicate any of these drugs,
including chloroquine, are actually helpful in treating this new virus Covid19.
Chloroquine and Hydroxychloroquine,A closely related drug seem to suppress the growth of
coronavirus in laboratory studies in test tubes, so to speak, says David Juurlink, the chairman
of clinical pharmacology and toxicology at the Sunnybrook Health Sciences Center in Toronto,
Whether or not they do anything of value for people infected with the coronavirus is not at all
clear.” That is, just because something works in a very specific lab setting doesn’t always mean it
will work in the human body in the same way.
These drugs are approved to treat malaria, lupus, and rheumatoid arthritis—none of which are
conditions caused by a virus. In the small studies that have been done to date, scientists have
found that the drugs interfere with the virus’s ability to bind to host cells and self-replicate inside
the host.
But it’s far from certain that these drugs would be effective in treating people who have
COVID-19. “It’s one thing to show that a drug suppresses the growth of a virus in a laboratory
experiment,” says Juurlink. “It’s quite another thing to show that the benefits of a drug in a
person outweigh the potential harms of the drug—and every drug contains potential harms.”
For Chloroquine and Hydroxychloroquine, he said, those harms are potentially severe. At the top
of the list is the fact that the drug is toxic if ingested in doses even slightly higher than the levels
recommended for therapeutic treatment.
“A couple tablets of these drugs could kill a small child,” Juurlink says. “There’s a fine line
between what the [effective] treatment dose is and what the toxic dose is.” these drugs can have
serious side effects, including irregular heartbeat, a drop in blood sugar, mood changes and even
psychosis, and negative interactions with other drugs.
No drugs have currently been approved by the FDA to treat COVID-19, the agency said in a press
release following President Donald Trump’s factually incorrect statement that chloroquine had
been granted approval.
The FDA isn’t ignoring a potentially useful drug.The agency is looking into whether the drug could
“potentially reduce the duration of symptoms, as well as viral shedding, which can help prevent
the spread of disease,”
If that turns out to be the case, for someone with COVID19, the potential aid of taking
Chloroquine or Hydroxychloroquine could outweigh the risks associated with these drugs. But
there’s no clue yet that is the case.
The president’s remarks prompted some people {including some doctors} to start stocking
up on Chloroquine and even taking it preemptively to stall a COVID-19 infection. All of this
misinformation and premature hype over the drug has had dramatic consequences. A man in

Arizona died over the weekend after taking Chloroquine phosphate which is intended for use in
Fish tanks but has the same active ingredient as the one being inspected for COVID19.
Although there is no drug has approved for treating COVID19 yet, Jurlink says it’s likely the
situation will change in the next weeks and months. I understand panic buying toilet paper and
hand sanitizer too,” he says. “But these medications should not be in the same category, and I
would encourage people to wait and see what science says about the usefulness, if any, of these
drugs.”
At the same time, reports of people already on chloroquine for autoimmune conditions like lupus
show that the drug is already in short supply for these patients. As BoredPanda reported this
week, a woman with lupus was told by Kaiser Permanente, her healthcare provider, that her
medication would be withheld indefinitely. In an email to BoredPanda, Kaiser Permanente
confirmed that, for now, it would no longer be filling prescriptions for chloroquine. Lupus is a
lifelong condition with no cure, marked by periods of flare-ups and remission. Chloroquine is
used as a maintenance therapy to prevent these flares. Stopping this maintenance drug could
put a person at a higher risk of a flare-up which could land them in the hospital.
It’s important for the public to understand there is a lot of research going on this critical issue,
he says. So feel relax, follow public health advisories, and remember: The best things you can do
right now are wash your hands and avoid social, cultural and religious gatherings.

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